SULGIN AVEXIMA
- Registration number:ЛСР-000845/10
- International non-proprietary name:sulfaguanidine
- Pharmaceutical form:tablets
- Pharmacotherapeutic group:antimicrobial agent - sulfanilamide
- Dosage form:tablets 500 mg No. 10 and No. 20
- Composition:active substance: sulfaguanidine monohydrate (sulgin) - 500 mg
SULGIN AVEXIMA is an antimicrobial bacteriostatic agent. It inhibits the growth of coliform bacteria, and reduces the intestinal synthesis of thiamine, riboflavin, nicotinic acid.
A high bacteriostatic drug concentration appears in the intestine. SULGIN produces a bacteriostatic action against Streptococcus spp., Staphylococcus spp., Escherichia coli, Shigella dysenteriae, Proteus vulgaris.
- Indications for use:
-
- bacillary dysentery;
- colitis and enterocolitis;
- preparation for a large bowel surgery.
- Dosing schedule:
-
- in acute dysentery:
— For adults
2 treatment courses are given.
The first course:
Days 1 and 2 - 1 g (2 tablets) every 4 h (totally, 6 g/day);
Days 3 and 4 - 1 g every 6 h (4 g/day);
Days 5 and 6 - 1 g every 8 h (3 g/day).
If required, after 5-6 days, the second course is given.
The second course:
Days 1 and 2 - 1 g every 4 h, at night - after 8 h (totally, 5 g/day);
Days 3 and 4 - 1 g every 4 h (4 g/day), not to be taken at night;
Day 5 - 3 g/day.
- For children over 3 years old
0.5 g (1 tablet) 4 times daily for 7 days.
- in acute dysentery:
-
- in treatment of other infections:
— For adults
Day 1 — 1-2 (2-4 tablets) every 4-6 h.;
subsequent 2-3 days — half-doses.
— For children over 3 years old
Day 1 - 0.1 g/kg/day in equal doses every 4 h;
on subsequent days — 0.25-0.5 g every 6-8 h.
- prophylaxis of postoperative intestinal complications:
0.05 g/kg every 8 h for 5 days before and 7 days after the surgery.
The highest doses for adults: a single dose - 2 g; a daily dose - 7 g.
- in treatment of other infections:
- Shelf life:
-
4 years. Do not use after the expiry date.
- Manufacturer
- OJSC "Irbitsky Chemical-Pharmaceutical Plant"
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