SULGIN AVEXIMA

Registration number:ЛСР-000845/10
International non-proprietary name:sulfaguanidine
Pharmaceutical form:tablets
Pharmacotherapeutic group:antimicrobial agent - sulfanilamide
Dosage form:tablets 500 mg No. 10 and No. 20
Composition:active substance: sulfaguanidine monohydrate (sulgin) - 500 mg

SULGIN AVEXIMA is an antimicrobial bacteriostatic agent. It inhibits the growth of coliform bacteria, and reduces the intestinal synthesis of thiamine, riboflavin, nicotinic acid.

A high bacteriostatic drug concentration appears in the intestine. SULGIN produces a bacteriostatic action against Streptococcus spp., Staphylococcus spp., Escherichia coli, Shigella dysenteriae, Proteus vulgaris.

Indications for use:

bacillary dysentery;
colitis and enterocolitis;
preparation for a large bowel surgery.

Dosing schedule:

in acute dysentery:

— For adults
2 treatment courses are given.

The first course:
Days 1 and 2 - 1 g (2 tablets) every 4 h (totally, 6 g/day);
Days 3 and 4 - 1 g every 6 h (4 g/day);
Days 5 and 6 - 1 g every 8 h (3 g/day).
If required, after 5-6 days, the second course is given.

The second course:
Days 1 and 2 - 1 g every 4 h, at night - after 8 h (totally, 5 g/day);
Days 3 and 4 - 1 g every 4 h (4 g/day), not to be taken at night;
Day 5 - 3 g/day.

- For children over 3 years old
0.5 g (1 tablet) 4 times daily for 7 days.

in treatment of other infections:

— For adults
Day 1 — 1-2 (2-4 tablets) every 4-6 h.;
subsequent 2-3 days — half-doses.

— For children over 3 years old
Day 1 - 0.1 g/kg/day in equal doses every 4 h;
on subsequent days — 0.25-0.5 g every 6-8 h.
prophylaxis of postoperative intestinal complications:
0.05 g/kg every 8 h for 5 days before and 7 days after the surgery.