BISOPROLOL AVEXIMA
- Registration number:ЛП-002861
- International non-proprietary name:bisoprolol
- Pharmaceutical form:film-coated tablets
- Pharmacotherapeutic group:beta-1 selective blocker
- Dosage form:film-coated tablets 5 mg No. 30, film-coated tablets 10 mg No. 30
- Composition:active substance - bisoprolol fumarate (calculated as 100 % substance) - 5 mg or 10 mg.
Bisoprolol is a beta-1 selective blocker without its own sympathomimetic activity, it does not have membrane-stabilizing action.
The medicinal product produces an antihypertensive, antiarrhythmic, and antianginal action.
When it is used at medium therapeutic doses, compared to non-selective beta-blockers, the medicinal product exerts less prominent effect on the organs containing beta₂-adrenergic receptors (pancreas, skeletal muscles, smooth muscles of peripheral arteries, bronchi, and uterine) and on carbohydrate metabolism; it does not lead to retention of sodium ions within the body; the degree of atherogenic effect does not differ from that of propranolol.
- Indications for use:
-
Combination therapy:
- arterial hypertension;
- ischemic heart disease (IHD): prevention of stable angina episodes;
- chronic heart failure (CHF);
- Method of administration and posology:
- For oral use, once daily, under fasting condition in the morning. The dose is selected individually by the doctor.
-
- treatment of arterial hypertension and angina - starting dose is 5 mg; if required, the dose is increased up to 10 mg. Maximal daily dose is 20 mg.
- treatment of stable CHF - starting dose is 1.25 mg; subsequent dose increase - up to 2.5 mg, 3.75 mg, 7.5 mg, and 10 mg. Each subsequent dose increase - not earlier than in 2 weeks. Maximal recommended dose is 10 mg.
- treatment of arterial hypertension and angina - starting dose is 5 mg; if required, the dose is increased up to 10 mg. Maximal daily dose is 20 mg.
- Shelf life:
-
2 years. Do not use after the expiry date.
- Manufacturer
- OJSC "Irbitsky Chemical-Pharmaceutical Plant"
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