Plant history

Chemical and Pharmaceutical Plant was founded in Anzhero-Sudzhensk town in 1942 on the basis of the relocated Moscow Chemical and Pharmaceutical Plant n.a. Semashko.

1940-1970th - The plant is known as one of the largest manufacturers of drug substances in the country. The products were exhibited and awarded many times. In 1970th the plant exhibited its products in 25 countries across the world.

1980th - Manufacturing of solid non-sterile drug formulations based on own-manufactured substances has been set up since 1986.

1990th - In 1992 the plant was renamed as Asfarma Joint-Stock Company of the Open Type (JSCOT) followed by reorganization into Asfarma Open Joint Stock Company (OJSC).

2000th - In 2001 the building for tablet manufacturing was renovated. Clean rooms were built for the first time.

In 2005 the legal entity was changed with establishment of Asfarma LLC

In 2008 manufacturing of infusion solutions was launched along with manufacturing of medical devices and PVC containers

2012 - Asfarma LLC conducts business as a production unit of Avexima JSC. The company policy is aimed at expansion of manufacturing of total synthesis of active pharmaceutical ingredients, finished dosage forms and infusion solutions both according to volume and nomenclature.

Quality management system at the company was implemented and certified for compliance with regulatory requirements of ISO 9001

2013 - In the workshop for finished medicinal products, a clean room complex CRC-1 for tablet manufacturing with a production capacity of 4.5 mln packages per month was set in operation. The site is equipped with the equipment of the leading European manufacturers.

CRC-С site for secondary packaging of suppositories and ampoules was arranged

License to perform activities associated with distribution of narcotic drugs, psychotropic substances and its precursors was obtained

Asfarmochka canteen with a seating capacity of 100 places fitted with modern equipment was built and set in operation for company employees and city residents.

2014 - The company was renamed as Anzhero-Sudzhensk Chemical and Pharmaceutical Plant LLC.

Reequipment of synthesis site with equipment modernization was performed. Clean rooms with crystallization and drying stage with installation of modern equipment in accordance with the requirements of Good Manufacturing Practice Requirements were arranged. This reequipment allowed arranging new manufacturing of phenobarbital substance with a capacity of 10 tons annually.

2012-2014 Infusion solution workshop was renovated and upgraded.

Manufacturing of new products - powder and suppositories - was mastered.

2014-2015 Electrical Control & Instrumentation workshop was arranged based on the existing buildings; here the mechanical repair department was located, a new health center was built. A laundry corresponding to all current standards was opened.

2015-2016 Modern warehouses with an area of 3000 m2 for storage of raw and other materials, finished products, complying with the requirements of Good Manufacturing Practices were arranged and equipped with new technical devices

QC was equipped with new laboratory equipment allowing for control using new up-to-date test methods for solid, liquid medicinal products, suppositories providing high reliability and ruggedness in work.

2016 CRC-2 site for tablet production with a capacity of 9 mln packages per month was reequipped, activated carbon site (CRC-4) fitted with the new generation equipment was arranged.

The site for powder filling in polymer jars (CRC-C) fitted with new generation equipment was arranged

The site for activated carbon substance production was arranged

The site for Polymer Jar medical device production was set in operation at the polymeric device site.

The Conclusion of the Ministry of Industry and Trade of the Russian Federation about compliance with the requirements of Good Manufacturing Practices was obtained.

2017 Anzhero-Sudzhensk Chemical and Pharmaceutical Plant LLC was renamed as Avexima Siberia LLC.

In 2017 Avexima Siberia LLC celebrated its 75th anniversary